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Anti -IGF1 Receptor Rabbit pAb

貨號:GB111631

品牌:Servicebio

價格:¥650

規格: 100 μl

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Product Information

 

Description IGF1 Receptor rabbit polyclonal
Protein full name Insulin-like growth factor 1 receptor
Synonyms Insulin-like growth factor I receptor, IGF-I receptor, CD221, MGC142170, JTK13, CD221 antigen, IGFIRC, Insulin like growth factor 1 receptor precursor
Immunogen KLH conjugated Synthetic peptide
corresponding to Mouse IGF1 Receptor
Isotype IgG
Purity Affinity purification
Predicted MW. 155 kDa
Observed MW. 95 kDa
Uniprot ID P08069, Q60751, P24062

 


 

Applications

 

Applications Species Dilution Positive Tissue
WB Human, Mouse, Rat 1: 500-1: 1000 testis

 


 

Background
 

IGF1R, also named as CD221, is a receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). IGF1R binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity, the activated IGF1R is involved in cell growth and survival control. It is crucial for tumor transformation and survival of malignant cell. IGF1R is a heterotetrameric receptor, composed of two alpha subunits (130 kDa each) and two beta subunits (~98 kDa each) .

 


 

Images

 


Western blot analysis of IGF1R(GB111631) 
at dilution of 1: 1000
Lane 1: Hela cell lysate
Lane 2: HepG2 cell lysate
Lane 3: C2C12 cell lysate
Lane 4: Mouse testis tissue lysate
Lane 5: Rat testis tissue lysate
 

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.
 

 

NOTE: This product is intended for research only.

 

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